For decades, Ghana’s television screens have been blessed with unforgettable duos, pairs whose chemistry, wit, and sheer talent shaped the nation’s entertainment landscape.
Whether on stage, film, radio, or TV, these combos gave Ghanaians countless reasons to laugh, love, argue, reflect, and tune in week after week.
In this nostalgic journey, The Ghana Report takes you down memory lane to revisit the remarkable partnerships that once held the nation spellbound, pairings whose artistry has been woven into the very fabric of Ghanaian popular culture.
Bob Santo & Judas — The gold standard of comedy

Arguably the most beloved comedic pair in Ghanaian history, the late Bob Santo (John Evans Bosompem) and Judas (Abubakar Kwame Amponsah) dominated the Concert Party era and early television comedy.
Their effortless chemistry and rib-cracking delivery remain unmatched, setting a benchmark for all who came after.
Agya Koo & Mercy Asiedu / Kyeiwaa — Kumawood’s classic combos

At the height of Kumawood’s popularity, Agya Koo’s collaborations with Mercy Asiedu and Rose Mensah (Kyeiwaa) became household favourites.
Their scenes, usually filled with domestic banter, witty clashes, and humour rooted in everyday life, were irresistible to fans across the country.
Majid Michel & Jackie Appiah — The reigning royals of romance

The “Ghallywood” wave brought with it Majid Michel and Jackie Appiah: a duo whose on-screen romance travelled beyond Ghana’s borders.
Their stories of love, heartbreak, and redemption captivated West Africa and helped define an era of modern Ghanaian cinema.
Adjetey Anang & Lydia Forson — Chemistry with purpose

A more recent pairing, Adjetey Anang and Lydia Forson, earned critical acclaim for films like Keteke.
Their heartfelt depiction of a couple racing against time to welcome their baby felt real, raw, and deeply Ghanaian.
Lil Win & Akrobeto — Masters of unexpected chaos

When Kumawood needed comedic relief, Kwadwo Nkansah (Lil Win) and Akrobeto delivered in full force.
Their unpredictable antics, exaggerated reactions, and unfiltered humour built a comedic bond that still entertains viewers to this day.
John Dumelo & Yvonne Nelson / Jackie Appiah — Modern screen classics

In the late 2000s to early 2010s, “Ghallywood” thrived on the magnetic pull between John Dumelo and either Yvonne Nelson or Jackie Appiah.
Their emotive performances remain some of the most rewatched Ghanaian films online in the last decade.
Dada Boat & Aboagye — The hustler and the hype

Micky Osei-Berko (Daddy Boat) and George Quaye (Aboagye) became the heartbeat of the early-2000s sitcom Dada Boat, a delightful spin-off of Taxi Driver.
With scams gone wrong and street-smart tricks, the series was a comedic mirror of Accra’s urban hustle.
David Dontoh & Grace Omaboe (Maame Dokono) — A pair too real to ignore

In the 2000s, their on-screen couple roles had viewers so convinced of their chemistry that rumours of an off-screen romance spread quickly. Even after David Dontoh clarified the speculations, the duo’s legacy as one of Ghana’s most believable pairings remains intact.
Presenting duos who ruled the airwaves
Bola Ray & the Joy FM drive time team — A crew like no other

Though Bola Ray was the main voice, his supporting team added flavour, synergy, and spontaneity that made Joy FM’s Drive Time a national obsession for years.
Nana Ama McBrown & her United Showbiz squad

On UTV’s United Showbiz, Nana Ama McBrown brought her charm and boldness to a dynamic panel of rotating entertainers.
Week after week, their lively debates and laughter turned the show into one of Ghana’s favourite Saturday-night rendezvous.
Kwame Sefa Kayi & Nana Yaa Konadu — Morning radio royalty

For years, this duo powered “Kokrokoo” on Peace FM. While Sefa Kayi anchored with calm authority, Nana Yaa Konadu’s “Masefo” segment gave listeners the relatable, down-to-earth edge they cherished.
Bola Ray & Anita Erskine — The power pair

Their commanding presence on Starr FM’s Drive Time made them the ultimate radio tag team of the mid-2010s as professional, energetic, and always engaging.
Captain Smart & Nana Yaa Brefo — The bold and the unfiltered

From Adom TV to Onua TV, this duo delivered unapologetic commentary that turned morning television into a lively, sometimes heated, national conversation.
These pairings across acting, radio, and television did more than entertain.
They shaped cultural memories, sparked conversations, and created characters and moments that still live in Ghana’s collective nostalgia.
Their stories remind us that when the right two talents meet, magic happens, magic that lights up screens, warms hearts, and defines eras.